04/01/2010 - News

Aspirin Use is Cost-Effective in Newly Diagnosed Diabetes

By: June Chen, MD


People with diabetes have a 2-4 times greater risk of developing cardiovascular disease than those without diabetes. Currently, the American Diabetes Association recommends aspirin therapy for people with diabetes over the age of 40 years. According to a study published online in Diabetes Care, people with newly diagnosed diabetes gain almost 4 months of life if they take aspirin.

Investigators from the Centers for Disease Control and their colleagues used a validated model to assess the long-term cost-effectives of aspirin use among adults at least 40 years of age who were newly diagnosed with type 2 diabetes. This model simulates the progression of diabetes and its associated complications and predicts outcomes related to these complications. The researchers found that, over a lifetime, adults with newly diagnosed diabetes who took 80 mg of aspirin daily gained 0.31 life years over non-aspirin users at a cost of $1700. In addition, people who received aspirin lowered their risk of coronary heart disease and death from coronary heart disease. However, aspirin users did have a 0.51% increase in the risk of stroke and a 0.28% increase in the risk of death from stroke.

Although aspirin use among adults with newly diagnosed diabetes is cost-effective, the investigators pointed out that it was not, in fact, cost-saving. In the model, people withtype 2 diabetes who took aspirin had higher costs for gastrointestinal bleeding, and their longer lifespan also resulted in the need for additional resources related to treatment of diabetes and high blood pressure. Based on these findings, the investigators that the use of aspirin to prevent cardiovascular disease in people with diabetes is still controversial and warrants further study, especially because 2 large trials recently showed that low-dose aspirin use in people with newly diagnosed diabetes did not lower the incidence of cardiovascular events.



Diabetes Care. Published online 23 March 2010.


Created on: 04/01/2010
Reviewed on: 04/01/2010

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