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Predicting kidney disease in diabetics

09/02/2002 - News

Predicting kidney disease in diabetics

By: Susan Aldridge, medical journalist, PhD

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Insulin resistance is a strong risk factor for kidney complications among people with type 1 diabetes.

Researchers at the University of Pittsburgh have been following a group of nearly 500 people with childhood-onset (type I) diabetes. As with type 2 diabetes, which starts later in life, kidney disease is a common complication in those with this condition.

It's always been assumed that the kidney problems are a consequence of high blood sugar over the long-term. But the Pittsburgh team have now shown that it is those diabetics with insulin resistance who are most likely to suffer from kidney disease. They used a novel method to measure insulin resistance - a combination of waist-to-hip ratio, hypertension and long-term blood sugar levels. This correlated well with lab tests for insulin resistance.

The good news is that not all type I diabetics are insulin resistant, so they may escape complications. And those who do have insulin resistance can probably improve their condition by exercise, healthy diet and quitting smoking.

Source

Kidney International September 2002

Created on: 09/02/2002
Reviewed on: 09/02/2002

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