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Lowering blood pressure key to treating kidney disease

12/12/2005 - News

Lowering blood pressure key to treating kidney disease

By: Susan Aldridge, medical journalist, PhD

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Lowering blood pressure key to treating kidney disease

Reported by Susan Aldridge, PhD, medical journalist

It is the lowering of blood pressure, rather than the drug used to acheive this, which is the main factor in treating kidney disease.
There are various drugs used to treat high blood pressure. Guidelines suggest that angiotensin-converting enzyme (ACE) inhibitors and angiotensin-II-receptor blockers (ARB) be first-line treatment blood pressure-lowering therapy among those with kidney disease. That's because it's thought they have a protective effect on the kidney over and above lowering blood pressure.

Researchers at the Centre for Clinical Pharmacology, University College, London, reviewed 127 clinical trials involving the effect of various blood pressure-lowering drugs on the progression of kidney disease. They conclude that it is the blood pressure lowering itself, rather than the drug used, which is important. Therefore ACE inhibitors and ARBs should only be prescribed if they are well tolerated and effective in the individual patient.

Source
The Lancet 10th December 2005

Created on: 12/12/2005
Reviewed on: 12/12/2005

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