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Table of Contents > Drugs >  Metronidazole
Metronidazole
Pronunciation
Brand Names
Foreign Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(me troe NI da zole)

Brand Names
Flagyl®; Flagyl ER®; MetroCream®; MetroGel® Topical; MetroGel®-Vaginal; Metro I.V.® Injection; MetroLotion®; Noritate™ Cream; Protostat® Oral

Foreign Brand Names
Ameblin (Mexico); Apo-Metronidazole® (Canada); Flagenase® (Mexico); Milezzol (Mexico); Novo-Nidazol (Canada); Otrozol (Mexico); Vatrix-S® (Mexico); Vertisal (Mexico)

Therapeutic Categories
Amebicide; Antibiotic, Topical; Antibiotic, Miscellaneous; Antiprotozoal

What key warnings should I know about before taking this medicine?

  • Talk with healthcare provider.


Reasons not to take this medicine

  • If you have an allergy to metronidazole or any other part of the medicine.
  • If you are in your first 12 weeks of pregnancy.


What is this medicine used for?

  • This medicine, when taken by mouth, is used to treat a variety of infections.
  • As a skin cream or gel it is used to treat acne rosacea. It may take 3-9 weeks to see full benefit.
  • As a gel, it is used to treat vaginal infections.


How does it work?

  • Metronidazole causes death of the cells causing the infection.


How is it best taken?

  • To gain the most benefit, do not miss doses.
  • Take entire prescription as directed even if feeling better.
  • Oral:
    • Take with or without food. Take with food if this medicine causes an upset stomach.
    • Do not take antacids with this medicine.
  • Skin:
    • Do not take by mouth. For skin only. Keep out of mouth, nose, and eyes (may burn).
    • Wash your hands before and after use.
    • Clean affected area before use.
    • Use a small amount over the area affected as a light film. Rub in gently.
  • Vaginal:
    • Use gel vaginally only.
    • Do not have sexual intercourse while using this medicine.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.


What are the precautions when taking this medicine?

  • Avoid all alcohol (includes wine, beer, and liquor). Can cause a bad reaction.
  • This could include flushing, headache, nausea, vomiting, sweating, or rapid heartbeat. Do not take alcohol for at least 24 hours after the last dose.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Do not use in the first trimester of pregnancy.
  • Birth control pills may not work. Use another form of birth control while on this medicine.
  • Do not use if you are breast-feeding.
  • Oral:
  • Tell healthcare provider if on phenytoin, phenobarbital, warfarin, lithium, or cimetidine.


What are the common side effects of this medicine?

  • Lightheadedness or dizziness. Use caution when driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Diarrhea. Yogurt, Bifidobacterium bifidum , or Lactobacillus acidophilus may help. These products are available at health food stores or in some pharmacies.
  • Headache. Mild pain medicine may help.
  • Not hungry or change in taste. Food may have a metal-like taste.
  • Can change urine to black or dark brown.
  • Skin:
    • Redness, dryness, burning, or irritation.


What should I monitor?

  • Condition being treated. Is it better, worse, or about the same.
  • Oral:
    • Watch for change in temperature or worsening of infection if you are being treated for an active infection.
    • If on warfarin, get INR checked within 1 week.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, throat.
  • Numbness or pain of the hands or feet.
  • Any rash.
  • Worsening of condition or feeling worse.


How should I store this medicine?

  • Store in a tight container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.

  
  

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